Current Clinical Trials Patients are invited to work with us so that together we may refine and improve medical and surgical treatments. Two full-time study coordinators Laura Trachtenberg, MS, and Anna Williford, RN, as well as Wendy Kaiser, RN, administer these studies.

Anna Williford, RN, and a patient discuss a research study.

Digestive Surgergy Research Laboratory | Pediatric Surgery Research Laboratory

Digestive Surgery Research Laboratory
Through the Digestive Surgery Research Laboratory, patients of University of Louisville's Section of Colon & Rectal Surgery have the opportunity to participate in research by enrolling in clinical trials. Below are trials that have been open to patient accrual over the last year, many of which are still ongoing. To learn more about our ongoing studies, please contact our research coordinator Anna Williford, RN, at (502) 583-0880.

"A Phase 2/3 Multicenter, Randomized, Placebo-Controlled, Double-Blind Study to Evaluate the Safety and Efficacy of Golimumab Induction Therapy, Administered Intravenously, in Subjects with Moderately to Severely Active Ulcerative Colitis."
PI: Galandiuk, S.
(Sponsor: Centocor)

"A Phase 3 Multicenter, Randomized, Placebo-Controlled, Double-Blind Study to Evaluate the Safety and Efficacy of Golimumab Maintenance Therapy, Administered Subcutaneously, in Subjects with Moderately to Severely active Ulcerative Colitis."
PI: Galandiuk, S.
(Sponsor: Centocor)

"Prospective Real-World Observational Outcomes of Flexi-Seal^® FMS (PROOF) in the Management of ICU Patients with Transient Fecal Incontinence."
PI: Galandiuk, S.
(Sponsor: ConvaTec)

"A 5-Year, Non-Interventional Registry Study of HUMIRA® (Adalimumab) in Patients with Moderately to Severely Active Crohn’s Disease (CD)."
PI: Galandiuk, S.
(Sponsor: Abbott Laboratories)

"Prospective open-label study of a smokeless tobacco product in Crohn's disease patients with moderately to severely active Crohn's disease who have failed prior attempts at smoking cessation"
PI: Galandiuk, S.
(Sponsor: Foundation for Clinical Research in IBD)

"The Association of Gastrointestinal Disease, DNA Repair and Host Defense Genes"
PI and Sponsor: Dr. Galandiuk

"Anorectal Motility in Patients with Crohn's Disease"
PI and Sponsor: Dr. Galandiuk

Return to Top

Pediatric Surgery Research Laboratory
At the Pediatric Surgery Research Laboratory, the following clinical studies, sponsored by Kosair Charities, are being conducted:

"Effects of Müllerian inhibiting substance on insulin receptor function in granulosa cells"
PI: Fallat, M.E.

"Role of Müllerian inhibiting substance in polycystic ovary syndrome: Effects of Müllerian inhibiting substance on granulosa cell function"
PI: Fallat, M.E.

"Serum and follicular fluid Müllerian inhibiting substance levels in women with polycystic ovary syndrome"
PI: Fallat, M.E.

"Ferriman-Galwey scoring system for adolescence: Evaluation of the Ferriman-Galwey scoring system for hirsutism in adolescent girls"
PI: Fallat, M.E.

"Müllerian inhibiting substance levels in diabetic adolescent girls and girls with insulin resistance"
PI: Fallat, M.E.

"Effects of Glucophage treatment on serum Müllerian inhibiting substance levels in diabetic adolescent girls and girls with insulin resistance"
PI: Fallat, M.E.

"Effects of Glucophage treatment on serum leptin in adolescent boys with insulin resistance"
PI: Fallat, M.E.

"Serum Müllerian inhibiting substance and prolactin levels during pregnancy"
PI: Fallat, M.E.

"Serum Müllerian inhibiting substance in women with diminished ovarian reserve"
PI: Fallat, M.E.

Return to Top